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applications of vibrational spectroscopy in pharmaceutical research and development
Don E. Pivonka, John M. Chalmers, Peter Griffiths (Autor)
·
wiley-interscience
· Libro Físico
applications of vibrational spectroscopy in pharmaceutical research and development - don e. pivonka, john m. chalmers, peter griffiths
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Origen: Reino Unido
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Reseña del libro "applications of vibrational spectroscopy in pharmaceutical research and development"
although vibrational spectroscopy is a critical technology within the pharmaceutical industry, currently the literature regarding its applications in the field is fragmented. at present there is no single volume that brings together the diverse aspects of vibrational spectroscopy at a level that will provide value to the dedicated spectroscopist as well as to the synthetic, development and medicinal based chemists, alike. this volume to aims to present key themes, established and emerging, within current research as well as presenting detailed contributions on the instrumentation, methodology, data treatment, and applications associated within this area of research. it will provide a consolidated road map to the practice of this science within the industry. contents: introduction; drug discovery discovery phase characterization of synthetic reactions and mechanisms using vibrational spectroscopy; vibrational applications in solid phase synthesis and combinatorial chemistry; spectra-property relationships; vibrational circular dichroism for the analysis of stereoisomers; drug development - analysis of pharmaceuticals and formulations; drug product investigations utilizing raman spectroscopy; polymorphism studies by vibrational spectroscopy; process vibrational spectroscopy in the pharmaceutical industry; nir imaging/microscopy; regulatory practices - iq/oq/pq (validation methods); nir spectroscopy in the pharma industry protocols and practices.
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